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Bevacizumab in epithelial ovarian carcinoma (Phase II).
| Variable | Cannistra (n = 44) (%) |
Garcia* (n = 70) (%) |
Burger (n = 62) (%) |
|---|---|---|---|
| Previous regimens | |||
| 1 | 100 | 34 | |
| 2 | 52 | ||
| 3 | 48 | ||
| Response rate | |||
| CR | 0 | 0 | 3 |
| PR | 16 | 24 | 18 |
| GI perforations | 11 | 6 | 0 |
| Arterial thrombosis | 7 | 4 | 0 |
| Bevacizumab-related deaths | 7 | 4 | 0 |
| Ref. | [8] | [9] | [7] |
Combined with oral cyclophosphamide.
CR: Complete response; GI: Gastrointestinal; PR: Partial response.
