. Author manuscript; available in PMC: 2009 Sep 15.

Published in final edited form as: J Urol. 2008 Jun 13;180(2):760–766. doi: 10.1016/j.juro.2008.03.187

Table 2.

EASE analysis of gene functional characteristics over-represented in the changed gene lists after knockdown of expression of Vcsa1.

System	Category	LH	LT	PH	PT	EASE
cellular component	integral to membrane	23	37	783	1932	0.0095
molecular function	receptor activity	14	43	375	2367	0.0264
molecular function	G-protein coupled receptor activity	8	43	159	2367	0.0348
molecular function	signal transducer activity	18	43	577	2367	0.0458

EASE analysis (http://david.niaid.nih.gov/david/ease.htm, (22)) of genes with changed expression following knock-down of Vcsa1 using siRNA at 25 nM. LH=List Hits (number of genes in the gene list that belong to the gene category. LT= List Total (number of genes in the gene list) PH=Population Hits (number of genes in the total group of genes assayed that belong to the specific gene category). PT= Population Total number of genes in the total group of genes assayed that belong to any category within the system).