Table 1.
Group demographics and clinical aspects of the subjects
| Normal Elderly (n = 11) | MCI (n = 9) | AD (n = 9) | |
|---|---|---|---|
| Age (mean) | 79.3 | 76.5 | 79.6 |
| Men/Women | 7/4 | 5/4 | 4/5 |
| Education (mean and range) | 12.9 (8,20) | 15.8 (12,20) | 13.8 (12,20) |
| Handedness R/L | 9/2 | 8/1 | 9/0 |
| CDR | 0 | 0.5 | 5 = .5/4 = 1.0 |
| CDR Sum of Boxes1 | 0 | .57 | 3.6 |
| MMSE1 | 29.1 | 28.4 | 23.4 (n = 8) |
| Mattis Dementia Rating Scale1 | 140.1 | 133.7 (n = 7) | 120.5 |
| AVLT % Retention1,2 | 12.2 | 6.4 (n = 7) | 5.2 |
| APOE, ε43 carrier/noncarrier/not available | 2/8/1 | 3/4/2 | 5/3/1 |
1
One-way ANOVA, p < .05, CDR not available in 2 MCI subjects
2
MOANS Age-corrected scaled scores (mean = 10, S.D. ± 3)
3
Subjects with a genotype of ε2/4 and ε3/4 were grouped as ε4 carriers; subjects with a genotype of ε2/3 and ε3/3 were grouped as ε4 noncarriers