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. 2009 Sep 23;4(9):e7139. doi: 10.1371/journal.pone.0007139

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Koehler et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Eighteen rhesus macaques were randomly divided among three groups: SIV/malaria, SIV-only, and malaria-only. There were five experimental animals and one uninfected control animal (*) in each group. On day 0 the malaria parasite infected animals were inoculated with Plasmodium cynomolgi, and the SIV infected animals were inoculated with SIV/Delta/B670 following the third parasite relapse (day 86).