Fig. 2.

Impact of Acute Total Sleep Deprivation on Reaction Time Performance. Time course of psychomotor vigilance task (PVT) performance [mean, median, 10% slowest and fastest reaction times in milliseconds (logarithmic scale)] during more than 28 hours of continuously monitored wakefulness under constant environmental and behavioral conditions are shown averaged across 10 subjects ± standard error of the mean. All data are binned from 10-minute PVT tests administered at 2-hour intervals and expressed with respect to elapsed time since wake time (designated as a Relative Clock Hour of 8), which was scheduled at its habitual hour. Figure and legend reprinted with permission from: Cajochen C, Khalsa SBS, Wyatt JK, Czeisler CA, Dijk D-J. Am J Physiol 277: R640–R649, 1999 (¹⁷).