Table I.

IL-17 cytokine family and functional effects on allergy

Ligands	Receptors	Functions	References
IL-17A	IL-17RA	IL-6, IL-8, IL-11, Gro-α, G-CSF and GM-CSF ↑	[53]
IL-17F	IL-17RA/C	MUC5AC and MUC5B ↑	[52]
		Airway hyper-reactivity ↑	[55]
		Neutrophilia ↑	[51]
		Severity of asthma ↑	[55]
IL-17E	IL-17RB	IL-4, IL-5, IL-13, IgE, and eotaxin ↑	[39,56,58,59,60.64]
		Mucus secretion ↑	[60,61]
		Airway hyper-reactivity ↑	[56,62,64]
		Eosinophilia ↑	[56,58,60,64]
		Severity of asthma ↑	[56,60,62,64]