Skip to main content
. Author manuscript; available in PMC: 2009 Sep 15.
Published in final edited form as: Free Radic Biol Med. 2008 Aug 8;45(9):1290–1301. doi: 10.1016/j.freeradbiomed.2008.08.002

Fig. 7.

Fig. 7

Role of ATP in GSH metabolism in α-syn N27 clones (A and B are in vitro data). (A) Effect of MG132 on GCL activity in the absence of exogenous ATP in α-syn-expressing vs untreated cells (C, control; W, wild type; M, A53T mutant). *p< 0.5 A53T compared to control cells; **p< 0.005 A53T compared to control cells. (B) Total ATP content in α-syn cells compared to control in the presence and absence of lactacystin (2.5 μM). *p< 0.001 compared to untreated A53T cells, ns, not significant compared to untreated cells.