Skip to main content
. Author manuscript; available in PMC: 2009 Sep 15.
Published in final edited form as: Clin Cancer Res. 2008 May 1;14(9):2647–2655. doi: 10.1158/1078-0432.CCR-07-1442

Table 3. Correlation between the Bb/pAb and mAb assays by markers and characteristics of the women in the serum subset (n=214).

Pearson's correlation coefficients between the mAb and Bb/pAb assays for each marker by case status, stage, and histology. The correlation coefficient quantifies the strength of the relationship between the mAb and Bb/pAb assays, where 1.0 indicates a perfect correlation between the assays.


Mesothelin bead-based assays
HE4 bead-based assays
Characteristics n r p-value r p-value
All Cases and Controls 214 0.8993 <0.001 0.8920 <0.001
Cases Only 71 0.9192 <0.001 0.9504 <0.001
Early Stage (stage I) 23 0.9147 <0.001 0.7885 <0.001
Stages II-IV
48
0.8955
<0.001
0.9493
<0.001
Healthy Controls 58 0.7440 <0.001 0.1508 0.2629
Benign Controls 53 0.7225 <0.001 0.4161 0.002
Surgical Controls
32
0.7943
<0.001
0.5293
0.002
Serous 44 0.8945 <0.001 0.9536 <0.001
Mucinous 6 0.8237 0.044 0.4914 0.3222
Endometrioid 6 0.8634 0.027 0.9905 <0.001
Clear Cell 5 0.9367 0.019 0.7118 0.178
Other Histologies 10 0.9078 <0.001 0.9548 <0.001