TABLE 1.

Whole blood cytokine production in response to 24-h LPS treatment at the beginning and end of a 1-y vitamin E supplementation trial in elderly nursing home residents¹

Cytokine	LPS	Group	n	Baseline	Follow-up
IL-1β	mg/L			ng/L
	1.0	Vitamin E	47	545 ± 384	461 ± 377*
		Placebo	63	547 ± 290	426 ± 232*
	0.01	Vitamin E	47	287 ± 231	254 ± 204
		Placebo	63	276 ± 179	237 ± 166
IL-6
	1.0	Vitamin E	47	8780 ± 5720	7787 ± 4319*
		Placebo	63	9045 ± 4812	7600 ± 4182*
	0.01	Vitamin E	47	5367 ± 3542	5084 ± 2569
		Placebo	63	5596 ± 2883	5059 ± 3051
TNFα
	1.0	Vitamin E	44	1476 ± 1884	769 ± 766*
		Placebo	61	1211 ± 1002	685 ± 638*
	0.01	Vitamin E	36	419 ± 464	389 ± 496
		Placebo	55	346 ± 317	329 ± 422

¹Data are unadjusted means ± SD. *Different from baseline, P < 0.05 (Student's t test of log-transformed data).