TABLE 3.
Whole blood TNFα production in response to 24-h LPS treatment at the end of a 1-y vitamin E supplementation trial in elderly nursing home residents by TNFα -308G > A genotype and supplementation group1
| LPS | Group | n | G/G | n | A/G, A/A | P-interaction2 |
|---|---|---|---|---|---|---|
| mg/L | ng/L | ng/L | ||||
| 1.0 | ||||||
| Vitamin E | 22 | 876 ± 840 | 17 | 749 ± 752a | 0.04 | |
| Placebo | 46 | 631 ± 643 | 10 | 967 ± 728b | ||
| 0.01 | ||||||
| Vitamin E | 18 | 495 ± 615 | 14 | 340 ± 346 | 0.18 | |
| Placebo | 40 | 327 ± 470 | 10 | 379 ± 313 | ||
1
Data are unadjusted means ± SD. Means in a column with superscripts without a common letter differ, P < 0.05 (Stratified analysis).
2
P-values for the interaction between vitamin E treatment and TNFα -308G > A, adjusted for baseline TNFα production.