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. 2009 Sep 6;9:15. doi: 10.1186/1472-6904-9-15

Table 6.

Quantitative drug use and potential drug-drug interactions at hospital admission and discharge

Admission Discharge
Total study population n = 102 Mean ± SDa Range Mean ± SDa Range P-valueb
Number of drugs per patient 10.9 ± 4.2 0-20 12.1 ± 4.3 2-21 <0.0001*
Number of pDDIsc per patient 1.9 ± 1.9 0-8 2.7 ± 2.5 0-11 <0.0001*
Number of pDDIsc per drug prescribed 0.2 ± 0.2 0-0.83 0.2 ± 0.2 0-0.64 0.0016*
TXd subgroup n = 49

Number of drugs per patient 12.6 ± 3.1 4-20 13.3 ± 3.2 5-20 0.055
Number of pDDIsc per patient 1.8 ± 2.4 0-8 2.7 ± 2.8 0-11 0.014*
Number of pDDIsc per drug prescribed 0.1 ± 0.1 0-0.53 0.2 ± 0.2 0-0,64 0.014*

Only pDDIs classified as moderate or severe were included in the analysis.

a SD = standard deviation

b p = statistical significance according to the t-test

c pDDIs = potential drug-drug interactions

d TX = transplantation

* Statistically significant