Table 6.
Admission | Discharge | ||||
Total study population n = 102 | Mean ± SDa | Range | Mean ± SDa | Range | P-valueb |
Number of drugs per patient | 10.9 ± 4.2 | 0-20 | 12.1 ± 4.3 | 2-21 | <0.0001* |
Number of pDDIsc per patient | 1.9 ± 1.9 | 0-8 | 2.7 ± 2.5 | 0-11 | <0.0001* |
Number of pDDIsc per drug prescribed | 0.2 ± 0.2 | 0-0.83 | 0.2 ± 0.2 | 0-0.64 | 0.0016* |
TXd subgroup n = 49 | |||||
Number of drugs per patient | 12.6 ± 3.1 | 4-20 | 13.3 ± 3.2 | 5-20 | 0.055 |
Number of pDDIsc per patient | 1.8 ± 2.4 | 0-8 | 2.7 ± 2.8 | 0-11 | 0.014* |
Number of pDDIsc per drug prescribed | 0.1 ± 0.1 | 0-0.53 | 0.2 ± 0.2 | 0-0,64 | 0.014* |
Only pDDIs classified as moderate or severe were included in the analysis.
a SD = standard deviation
b p = statistical significance according to the t-test
c pDDIs = potential drug-drug interactions
d TX = transplantation
* Statistically significant