Table 2.
Baseline Hemoglobin < 10 g/dL | Baseline Hemoglobin ≥10 g/dL | |||||
---|---|---|---|---|---|---|
Darbepoetin alfa 500 mcg Q3W N = 176 |
Darbepoetin alfa 2.25 mcg/kg QW N = 175 |
Difference (Q3W-QW) |
Darbepoetin alfa 500 mcg Q3W N = 177 |
Darbepoetin alfa 2.25 mcg/kg QW N = 177 |
Difference (Q3W-QW) |
|
Week 5 to EOTP K-M percent (95% CI) [N] | 36 (28 to 43) [164] | 41 (33 to 49) [167] | -5.1 (-16.1 to 5.9) | 14 (7 to 20) [171] | 21 (14 to 29) [170] | -7.3(-17.3 to 2.8) |
Week 1 to EOTP K-M percent (95% CI) | 44 (37 to 52) | 47 (39 to 54) | -2.3 (-13.2 to 8.6) | 14 (8 to 21) | 26 (18 to 33) | -11.3 (-21.4 to -1.2) |
Q3W = every three weeks; QW = weekly; EOTP = end of the treatment period (defined as the earlier of day 109 or end of study); K-M = Kaplan-Meier