Table 1.

Cerebral abnormal findings at the time of natural death or killing at the age of 69 weeks in SHRSP and WKY, and average lifespans with or without arundic acid medication

Rats/treatments	Cerebral findings at autopsy in six cases	Average life span (days)
SHRSP/control (n = 6)	Five cases of cerebral thrombosis, and one case of hemorrhage	273 ± 10.5
SHRSP/30 mg/kg/day arundic acid (n = 6)	Three cases of cerebral thrombosis, and one case of subarachnoidal hemorrhage (cf. three cases of heart failures with edema)	392.3 ± 18.1*
SHRSP/100 mg/kg/day arundic acid (n = 6)	One case of cerebral thrombosis, and two cases of subarachnoidal hemorrhage (cf. 3× survives)	>473.3 ± 7.4*
WKY	No brain lesion (cf. six cases of survives)	>483*

* Represents the significant differences at the level of p < 0.05 compared with SHRSP control group