Figure 1.
Schematic showing the filtration device. The device consists of a Delrin® mold (A), aluminum base (B), thermocouple (C), temperature controller (D), and heating element (E). The Delrin® mold is connected to the actuator of an Instron 8521 servohydraulic system (F) and cyclically loaded via an aluminum rod (G). The SBF level and maximum and minimum positions that the Delrin® mold is displaced to are labeled on the figure. Holes in the Delrin® mold that did not have a PLGA scaffold were plugged with rubber stoppers. 1 L of SBF solution is housed in the aluminum base during mineralization. The Delrin® mold can simultaneously cast sixteen 10–mm diameter scaffolds (or twenty-five 5-mm diameter scaffolds, not shown).