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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Glia. 2009 Nov 1;57(14):1553–1565. doi: 10.1002/glia.20869

Fig. 4.

Fig. 4

Effect of p402 and p70 on the production of nitrite and the expression of iNOS mRNA in primary microglia isolated from wild type, IL-12Rβ1 (−/−) and IL-12Rβ2 (−/−) mice. Microglia were stimulated with 10 ng/mL p402 and p70. A: After 24 h of stimulation, the production of nitrite was monitored by ‘Griess’ reagent. Data are mean + SD of three separate experiments. *P < 0.001 vs. control. After 6 h of stimulation, the expression of iNOS mRNA was monitored by RT-PCR (B) and quantitative real-time PCR (C). *P < 0.001 vs. control.