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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Glia. 2009 Nov 1;57(14):1553–1565. doi: 10.1002/glia.20869

Fig. 6.

Fig. 6

Role of Erk and p38 MAP kinases in p402-induced expression of iNOS in mouse BV-2 microglial cells. A: Cells were stimulated with 10 ng/mL p402 for different minute intervals. Activities of ERK (upper panel) and p38 (lower panel) MAP kinases were assayed by immuno-complex kinase assay. Cells preincubated with different concentrations of SB203580 and PD98059 for 30 min were stimulated with 10 ng/mL p402. B: After 24 h, supernatants were used for nitrite assay. **P < 0.05 vs. p402; *P < 0.001 vs. p402. C: After 6 h of incubation, Northern blot analysis for iNOS mRNA was carried out. D: After 24 h, viability was monitored by MTT assay. Data are mean + SD of three different experiments.