Scheme 2a.
a Reagents and conditions: (i) (a) NaH, DMF, rt; (b) (ClCH2CH2)2O. (ii) NaI, Me2CO, 65 °C. (iii) Methyl acrylate, Zn(Cu), EtOH-H2O, ultrasound, rt. (iv) 3 M HCl, reflux.
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