Skip to main content
. Author manuscript; available in PMC: 2009 Sep 16.
Published in final edited form as: J Med Chem. 2009 Jun 25;52(12):3652–3665. doi: 10.1021/jm8015798

Scheme 4a.

Scheme 4a

a Reagents and conditions: (i) NaOH, CH2Cl2, H2O, TEBAC, rt, Ar, 1 d. (ii) TFA/CH2Cl2/thioanisole, rt, 0.5 h. (iii) DBU, CH2Cl2, rt, 1 h. (iv) DBU, CH2Cl2, 50 °C, 6 h.