Table 3.
Summary of the Day-28 ACPR rates and difference (95% confidence intervals), the data is not PCR corrected.
| Day-28 Outcome | ACPR Rate | ACPR Difference (95% Confidence Intervals) | P value |
| ITT (missing = failure) | |||
| CPD (n = 422) | 63.7% | ||
| AL (n = 209) | 85.2% | ||
| SP (n = 210) | 50.0% | ||
| CPD vs SP | 13.7% (5.6%, 21.9%) |
0.001 | |
| AL vs CPD | 21.4% (14.8%, 28.1%) |
< 0.001 | |
| AL vs SP | 35.2% (26.9%, 43.5%) |
< 0.001 | |
| ITT (missing = success) | |||
| CPD (n = 422) | 79.4% | ||
| AL (n = 209) | 98.6% | ||
| SP (n = 210) | 70.5% | ||
| CPD vs SP | 9.4% (2.1%, 16.7%) |
0.01 | |
| AL vs CPD | 19.2% (15.0%, 23.4%) |
< 0.001 | |
| AL vs SP | 28.6% (22.2%, 35.0%) |
< 0.001 | |
| Per Protocol | |||
| CPD (n = 356) | 75.6% | ||
| AL (n = 181) | 98.3% | ||
| SP (n = 168) | 62.5% | ||
| CPD vs SP | 13.1% (4.5%, 21.6%) |
0.003 | |
| AL vs CPD | 22.8% (17.9%, 27.6%) |
< 0.001 | |
| AL vs SP | 35.8% (28.3%, 43.4%) |
< 0.001 | |