Table 4.
Summary of the Day-42 ACPR rates and difference (95% confidence intervals), the data is not PCR corrected
| Day-42 Outcome | ACPR Rate | ACPR Difference (95% Confidence Intervals) | P value |
| ITT (missing = failure) | |||
| CPD (n = 166) | 55.4% | ||
| AL (n = 82) | 75.6% | ||
| SP (n = 82) | 46.3% | ||
| CPD vs SP | 9.1% (-4.1%, 22.3%) |
0.224 | |
| AL vs CPD | 20.2% (8.2%, 32.2%) |
0.002 | |
| AL vs SP | 29.3% (15.0%, 43.5%) |
< 0.001 | |
| ITT (missing = success) | |||
| CPD (n = 166) | 72.9% | ||
| AL (n = 82) | 96.3% | ||
| SP (n = 82) | 69.5% | ||
| CPD vs SP | 3.4% (-8.7%, 15.4%) |
0.653 | |
| AL vs CPD | 23.4% (15.6%, 31.3%) |
< 0.001 | |
| AL vs SP | 26.8% (16.1%, 37.6%) |
< 0.001 | |
| Per Protocol | |||
| CPD (n = 137) | 75.6% | ||
| AL (n = 65) | 98.3% | ||
| SP (n = 63) | 62.5% | ||
| CPD vs SP | 6.8% (-7.6%, 21.3%) |
0.425 | |
| AL vs CPD | 28.2% (18.9%, 37.6%) |
< 0.001 | |
| AL vs SP | 35.1% (22.0%, 48.2%%) |
< 0.001 | |