TABLE I.
Treatment | Adrenal wt. (mg) | % Body wt. | Thymus wt. (mg) | % Body wt. | |
---|---|---|---|---|---|
P 11 | WEIGH | 7.24 ± 0.32 | 0.030 ± 0.001 | 94.66 ± 3.80 | 0.390 ± 0.011 |
SAL | 7.47 ± 0.32 | 0.030 ± 0.001 | 96.86 ± 3.79 | 0.388 ± 0.011 | |
MA | 7.21 ± 0.32 | 0.030 ± 0.001 | 92.46 ± 3.79 | 0.376 ± 0.011 | |
FS | 7.31 ± 0.32 | 0.030 ± 0.001 | 96.70 ± 3.79 | 0.391 ± 0.011 | |
ISO | 7.44 ± 0.32 | 0.031 ± 0.001 | 91.90 ± 3.79 | 0.379 ± 0.011 | |
P 15 | WEIGH | 10.84 ± 1.54 | 0.034 ± 0.004 | 135.40 ± 5.30 | 0.424 ± 0.013 |
SAL | 15.24 ± 1.53 | 0.047 ± 0.004 | 128.30 ± 5.29 | 0.409 ± 0.013 | |
MA | 8.89 ± 1.56** | 0.036 ± 0.004 | 82.61 ± 5.33**** | 0.329 ± 0.014**** | |
FS | 11.59 ± 1.54 | 0.038 ± 0.004 | 120.3 ± 5.23††† | 0.398 ± 0.013 | |
ISO | 11.40 ± 1.53 | 0.036 ± 0.004 | 132.3 ± 5.23 | 0.422 ± 0.013 |
Adrenal and thymus least square mean weights for weighed only (WEIGH), saline (SAL), (+)-methamphetamine (MA), forced swim (FS), and isolation (ISO) treatments for P11 and P15. For comparison, each tissue was normalized to body weight and expressed as the percentage of tissue per total body weight,
= P < 0.01,
= P < 0.0001 compared with all other treatments,
= P < 0.001 when compared with WEIGH and ISO.