Figure 1.

Diagrams showing the affinity based delivery system and cell culture process. A) Schematic of the affinity-based delivery system. The bidomain peptide becomes covalently cross linked into the fibrin scaffold during polymerization. This peptide contains heparin binding domain, allowing to non-covalently retain heparin inside of the scaffold. The heparin in turn non-covalently binds the growth factor, causing it to remain in the scaffold. B) Schematic of the process for producing embryoid bodies and followed by seeding and culture inside of fibrin scaffolds.