Table 3.
Statistical summary (Mean ± Standard Deviation) of image metrics and pulmonary function with asthma severity for subjects included in the regional analysis.
| Parameter | Severe (N=6) | Non-severe (N=15) | Overall (N=21) |
|---|---|---|---|
| Defect Score | 16.7±12.3 | 11.0±9.5 | 12.6±10.4 |
|
| |||
| Percent Defect Volume (%) | 7.6±4.2 | 5.4±4.5 | 6.0±4.4 |
|
| |||
| Expiratory densitometry: | |||
| Percent below −850 HU | 4.7±2.1 | 8.0±7.3 | 7.0±6.4 |
| Percent below −910 HU | 0.9±1.0 | 1.5±1.7 | 1.3±1.6 |
| Percent below −950 HU | 0.3±0.5 | 0.4±0.7 | 0.4±0.6 |
|
| |||
| FEV1 (% predicted) | 82.7±11.1 | 91.5±15.1 | 89.0±14.3 |
|
| |||
| FEF25–75 (% predicted) | 71.7±36.3 | 69.4±23.4 | 70.0±26.8 |
|
| |||
| FEV1/FVC (% predicted) | 94.4±13.6 | 89.2±8.6 | 90.7±10.2 |
|
| |||
| RV/TLC | 0.323±0.098 | 0.308±0.052 | 0.312±0.066 |
| BAL: | |||
| % Neutrophils | 0.86±0.86 | 2.48±2.93 | 2.01±2.58 |
| % Eosinophils | 0.74±0.73 | 0.63±0.67 | 0.66±0.67 |
| % Macrophage | 91.3±2.9 | 85.5±11.2 | 87.2±9.8 |