FIG. 1.
Antibody responses to LC16m8 and Dryvax. (A and B) Groups of mice (three per group) were inoculated with 106 PFU of LC16m8 (A) or Dryvax (B) by the intramuscular (I.M.), subcutaneous (S.C.), or percutaneous/tail scarification (Tail scarif) route. Serum samples were collected at intervals of 3 weeks and analyzed for vaccinia virus MV-specific IgG by ELISA by using inactivated Dryvax as an antigen. (C) Immune sera were tested for IgG isotype distribution. Error bars represent standard deviations.