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. Author manuscript; available in PMC: 2009 Oct 11.
Published in final edited form as: J Med Chem. 2009 Jun 11;52(11):3539–3547. doi: 10.1021/jm900116d

Figure 6. The principal cyanine aggregate formed in solution is a dimer.

Figure 6

Concentrations of monomeric (Cm) and aggregate (Ct-Cm) forms of 11, 12, and 5 were calculated from absorbance spectra and replotted on double logarithmic scales. Each point represents a spectrum collected at a different bulk compound concentration, whereas each line represents best fit of the data points to a linear regression. Regression slopes for 11, 12, and 5 were 2.3 ± 0.1, 1.8 ± 0.1, and 1.7 ± 0.1, respectively, consistent with dimerization being mostly responsible for the spectral shifts of all three compounds.