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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Circ Cardiovasc Genet. 2008 Dec 1;1(2):85–92. doi: 10.1161/CIRCGENETICS.108.793158

Table 4.

Association of rs2383206 genotype with extent, severity, and location of CAD in the incident event (population sets 1A and 1B) and the prevalent disease patients (sets 2A and 2B, excluding the non-CAD patients).

CAD Measure AA AG GG p-trend
Number of diseased vessels (mean)
 Set 1A 1.94 1.95 2.02 0.15
 Set 1B 1.88 1.83 1.89 0.87
 Set 2A 1.79 1.70 1.78 0.87
 Set 2B 1.74 1.72 1.78 0.57
Duke CAD Index (mean)
 Set 1A 46.4 47.0 48.5 0.10
 Set 1B 47.5 45.8 46.8 0.75
 Set 2A 44.7 43.8 45.4 0.42
 Set 2B 43.0 43.8 44.8 0.32
Left Main disease
 Set 1A 3.6% 3.5% 2.3% 0.26
 Set 1B 5.3% 6.2% 7.3% 0.36
 Set 2A 1.4% 2.9% 2.6% 0.49
 Set 2B 3.3% 5.2% 6.1% 0.20
Proximal disease
 Set 1A 31.3% 35.6% 32.5% 0.86
 Set 1B 47.1% 37.7% 39.7% 0.12
 Set 2A 35.9% 34.9% 42.9% 0.06
 Set 2B 40.6% 31.8% 38.9% 0.98
Ostial disease
 Set 1A 5.3% 6.5% 5.5% 0.99
 Set 1B 7.1% 7.7% 7.3% 0.95
 Set 2A 2.4% 4.5% 6.1% 0.048
 Set 2B 3.9% 5.0% 6.1% 0.29