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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: Nat Neurosci. 2009 Aug 16;12(9):1129–1135. doi: 10.1038/nn.2372

Figure 8. Loss of Drosophila LRRK increases the hypo-phosphorylated 4E-BP and partially suppresses parkin and PINK1 mutant phenotypes.

Figure 8

(a) Western blot analysis of levels of phosphorylated and non-phosphorylated 4E-BP. (b) Quantification of relative amounts of phosphorylated and non-phosphorylated 4E-BP after normalization for total levels of 4E-BP. The mean and SEM of three independent experiments are represented. Analysis of (c) dopaminergic neurons, (d) flight and (e) climbing in mutant combinations. Charts show mean and SEM. Wild type is park25/+; LRRK e03680/+.