Table 3. Thermodynamic Parameters of MO/RNA Dimers.
oligomera | Tm (°C) | ΔG (kcal/mol)b |
---|---|---|
ntla | 77.7 ± 0.8 | −28.1 ± 2.4 |
heg | 83.4 ± 0.9 | −28.4 ± 2.2 |
flh | 83.4 ± 0.8 | −27.5 ± 2.1 |
etv2 | 73.9 ± 1.0 | −25.1 ± 2.8 |
spt | 85.2 ± 1.2 | −30.0 ± 3.2 |
Dimers of 25-mer MO and RNA oligomers.
Binding free energy of the MO/RNA dimer at 28 °C.