Table 2.
Group | Cerebellar NOS Activity |
Renal Cortex NOS Activity |
Renal Medulla NOS Activity |
---|---|---|---|
Control NS | 29.27 ± 3.56 (100 ± 1) | 0.79 ± 0.07 (96 ± 3) | 0.88 ± 0.12 (84 ± 1) |
Control HS | 22.50 ± 4.31 (99 ± 2) | 0.91 ± 0.14 (92 ± 2) | 1.13 ± 0.19 (87 ± 2) |
AG + NS | 27.33 ± 7.90 (101 ± 1) | 0.65 ± 0.11 (95 ± 2) | 1.08 ± 0.07 (87 ± 1) |
AG ± HS | 28.85 ± 10.74 (102 ± 1) | 0.65 ± 0.09 (94 ± 2) | 1.06 ± 0.06 (89 ± 1) |
NS-2 | ND | 1.22 ± 0.12 | 1.40 ± 0.16 |
HS-2 | ND | 0.92 ± 0.12 | 1.46 ± 0.18 |
NS = normal salt intake (~0.6%; NS); HS = high NaCl intake (~6%) for 14 days; AG = rats chronically given AG by gavage (250 mg/kg/day) for 14 days; NS-2 and HS-2 = additional groups of rats fed normal salt (NS-2) and high salt (HS-2) diets, and studied for baseline renal NOS activity only; other abbreviations as in Table 1.
Data given as mean ± SE. Percent inhibition with L-arginine analogs given in parentheses. No values were different from control.