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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: Biochem Pharmacol. 2008 Nov 25;77(5):835–844. doi: 10.1016/j.bcp.2008.11.017

Fig. 1. Effect of G12/13 activation on 2MeSADP-induced platelet dense granule release in human platelets.

Fig. 1

Fig. 1

Aspirin-treated and washed human platelets were stimulated with 100 nM 2MeSADP, 60 μM YFLLRNP or 60 μM YFLLRNP+100 nM 2MeSADP at 37°C while stirring. Platelet aggregation (A) and secretion (B) were measured in a Lumi aggregometer. The tracings are representative of data from at least three independent experiments.