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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: Biochem Pharmacol. 2008 Nov 25;77(5):835–844. doi: 10.1016/j.bcp.2008.11.017

Fig. 3. Effect of selective activation of Phospholipase C and G12/13 pathways on platelet dense granule release in Gαq null mouse platelets.

Fig. 3

Fig. 3

Fig. 3

Fig. 3

Aspirin-treated and washed Gq−/− mouse platelets were stimulated with 80 μM m-3MFBS, 500 μM AYPGKF or 80 μM m-3MFBS+500 μM AYPGKF (A and B),100 nM 2 MeSADP, 500 μM AYPGKF or 100 nM 2MeSADP + 500 μM AYPGKF (C and D) at 37°C while stirring. Platelet aggregation (A and C) and secretion (B and D) were measured in a Lumi aggregometer. The tracings are representative of data from at least three independent experiments.