Table 1. Figures of merit for the FAIM-CTD structure.
Dihedral angles and NOE restraints were analyzed with PROCHECK (Laskowski et al., 1996)[26]. Qfree was computed using PALES as described in the text. Other statistics were calculated using CYANA.
| Restrictive NOE distance restraints (unique) | 934 |
| Short range | 399 |
| Medium range | 114 |
| Long range | 421 |
| TALOS dihedral angle restraints | 106 |
| Sidechain dihedral angle restraints | 37 |
| Hydrogen bond distance restraints | 16 |
| Dihedral angle statistics | |
| Residues in most favored regions | 78.9% |
| Residues in additionally allowed regions | 20.9% |
| Residues in generously allowed regions | 0.1% |
| Residues in disallowed regions | 0.2% |
| Average backbone RMSD to mean structure (residues T96 - T178) | 0.51 Å |
| Average heavy atom RMSD to mean structure (residues T96-T178) | 1.02 Å |
| Maximum NOE violation | 0.37 Å |
| Cornilescu Qfree from RDC validation (lowest-energy structure, secondary structural elements and turns only) | 0.505 |