Immunohistochemical staining of tumors for p63, Bcl-2, and Bcl-XL. Immunostaining for indicated antigens in brown, with hematoxylin counterstain. A, heterogeneity of staining patterns for p63 among tumors. Examples from four separate tumors. B, examples of p63, Bcl-2, and Bcl-XL staining in pretreatment biopsies of four additional tumors. H+E is conventional H&E staining. Each column, sections from a single tumor, with time to recurrence noted. From left to right: positive for Bcl-2, not Bcl-XL; positive for Bcl-2 and Bcl-XL; positive for Bcl-XL, not Bcl-2; negative for both Bcl-2 and Bcl-XL. Recurrence information only applies to panel B.