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. 2008 Sep;25(9):1087–1098. doi: 10.1089/neu.2007.0444

FIG. 7.

FIG. 7.

Cyp46 levels increase in microglia and astrocytes but not neurons 3 days following cortical injury. Relative levels of Cyp46 at the cell body of cells were compared to those in the contralateral cortex. (A) MAP-2-positive neurons at the site of injury did not show a significant change in Cyp46 levels, although levels tended to decrease (contralateral cortex, n = 139; injury site, n = 88). (B) Ox42-positive microglia at the site of injury showed an increase of 84% in Cyp46 levels (*Student's t-test, p < 0.0001; contralateral cortex, n = 62; injury site, n = 130). (C) GFAP-positive astrocytes at the site of injury did not show a significant change in Cyp46 levels, although levels tended to increase (contralateral cortex, n = 55; injury site, n = 57). Error bars (standard error of the mean).