Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2009 Aug 27;2:28. doi: 10.1186/1756-6606-2-28

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2009 Guilding et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Forskolin synchronizes cellular oscillators in the MBH. Plots showing cross correlations between pairs of oscillating cells in the ArcD (left) and DMHc (right). Correlations were calculated from raw data using a moving window (duration 48 h) with the test cell shifted in time between -24 and +24 hours. The color scale indicates the strength of correlation at any given point with 1 (dark red) indicating perfect correlation and -1 (dark blue) perfect anti-correlation. Initially the cells shown were weakly synchronized (ArcD) or exhibited different circadian periods (DMHc). After addition of forskolin at time 150 h, the periods of cellular oscillators synchronized (indicated by stronger vertical banding) and adopted a stable phase relationship either in phase (DMHc) or with one cell phase leading the other by ~6 h (ArcD).