Table 2.

Comparison of the localization-specific prediction results using BaCalLo independent dataset (BacelLo IDS)

		Animals				Fungi				Plants
Predictor	Loc	No.	SE	SP	MCC	No.	SE	SP	MCC	No.	SE	SP	MCC
MultiLoc2-LowRes	SP	75	97	97	0.89	9	78	98	0.60	6	83	95	0.58
	mi	48	89	97	0.81	77	68	94	0.62	6	67	96	0.51
	ch	-	-	-	-	-	-	-	-	72	77	94	0.72
	nu	224	62	93	0.57	152	63	79	0.36	36	91	90	0.77
	cy	85	72	82	0.43	180	54	78	0.27	17	41	94	0.38
	nu/cy	308	93	96	0.87	332	92	78	0.63	52	94	92	0.84
MultiLoc2-HighRes	SP	75	87	95	0.79	9	78	98	0.63	6	83	93	0.50
	mi	48	83	96	0.75	77	51	95	0.52	6	67	93	0.40
	ch	-	-	-	-	-	-	-	-	72	53	94	0.51
	nu	224	58	93	0.54	152	50	84	0.32	36	86	91	0.74
	cy	85	71	80	0.39	180	56	75	0.22	17	37	87	0.20
	nu/cy	308	91	91	0.78	332	84	76	0.48	52	93	84	0.74
BaCelLoc	SP	75	93	97	0.88	9	100	98	0.74	6	100	95	0.66
	mi	48	74	95	0.66	77	79	87	0.58	6	17	100	0.40
	ch	-	-	-	-	-	-	-	-	72	71	83	0.54
	nu	224	57	83	0.41	152	72	67	0.38	36	88	78	0.60
	cy	85	51	74	0.21	180	32	84	0.19	17	27	98	0.38
	nu/cy	308	93	92	0.83	332	85	83	0.61	52	88	84	0.70
LOCtree	SP	75	79	91	0.65	9	78	92	0.35	6	83	96	0.60
	mi	48	64	92	0.51	77	42	92	0.38	6	58	90	0.30
	ch	-	-	-	-	-	-	-	-	72	77	88	0.66
	nu	224	66	73	0.39	152	63	59	0.22	36	72	89	0.61
	cy	85	35	86	0.22	180	35	78	0.15	17	33	97	0.39
	nu/cy	308	84	83	0.64	332	83	49	0.31	52	75	93	0.70
Protein Prowler	SP	75	86	99	0.88	9	93	99	0.20	6	100	92	0.61
	mi	48	51	99	0.71	77	33	99	0.51	6	67	86	0.40
	ch	-	-	-	-	-	-	-	-	72	7	95	0.40
	nu/cy	308	98	73	0.79	332	98	40	0.52	52	86	77	0.52
TargetP	SP	75	88	98	0.88	9	89	97	0.56	6	100	93	0.61
	mi	48	82	92	0.63	77	50	92	0.44	6	50	91	0.26
	ch	-	-	-	-	-	-	-	-	72	55	91	0.49
	nu/cy	308	89	89	0.75	332	89	59	0.48	52	83	79	0.62
WoLF PSORT	SP	75	92	94	0.80	9	89	99	0.73	6	33	95	0.24
	mi	48	71	95	0.63	77	53	90	0.44	6	42	99	0.52
	ch	-	-	-	-	-	-	-	-	72	61	81	0.43
	nu	224	77	81	0.58	152	93	39	0.35	36	72	83	0.52
	cy	85	34	88	0.23	180	11	98	0.19	17	24	83	0.28
	nu/cy	308	89	90	0.76	332	89	57	0.46	52	87	74	0.61

The sensitivity (SE) and specificity (SP), given in percentages, and Matthews correlation coefficient (MCC) are listed for each localization (Loc). The number of clusters (No.) per localization is also shown. In Protein Prowler and TargetP, predictions for nu and cy are only available grouped as nu/cy.