. 2009 Sep 1;2:10. doi: 10.1186/1756-8935-2-10

Table 3.

Human polycomb phosphorylation sites

Complex	Drosophila	Name	Alternative symbol	Accession no.	Total no. of amino acids	Phosphosite	Conservation in Mouse	Refs
PRC2	E(z)	EZH1		Q92800	747	-	-	-
		EZH2		Q15910	746	S21	S21	[52]
						T339	T339	[102]
						S362	S362	[103]
						S363	S363	[103]
						S366	S366	[102,103]
						T367	T367	[102,103]
						S380	S380	[104]
						T487	T487^a	[102,103,105-110]
	Esc	EED		O75530	441	S25	S25	[102]^b
						S34	S34	[102]
						S43	S43	[102]^b
						S46	S46	[102]^b
						T50	T50	[102]^b
						T55	T55	[102]
						T57	T57	[102]
	Su(z)12	SUZ12		Q15022	739	S37	S37	[102]
						T131	T133	[111]
						S139	S141	[111]
						S382	S384	[103]
						T418	NC	[112]
						S541	S543	[102]
						S546	S548^a	[102,103,105,107,110]
						S583	S585^a	[103,107]
PRC1	Pc	CBX2	HPC1	Q14781	532	-	-	-
		CBX4	HPC2	O00257	558	Y205	Y207	[113]
						S347	S350	[102]^b
						T349	T352	[102]^b
						S413	S427	[110]
						T415	T412	[103]
						S430	S427	[107]
						T435	T432	[103]
						T495	NC	[38]
		CBX6		O95503	412	S107	S107	[103]
						S301	S302	[107]
						S303	S304	[107]
		CBX7		O95931	251	-	-	-
		CBX8	HPC3	Q9HC52	389	S110	S110	[102,108]^c
						S130	NC	[102]
						T234	T207	[102]^b
						S256	S229^a	[102,103]
						S265	S238^a	[102,103,108]^c
						S311	S284^a	^c
						S332	S305	[102,107]
						S352	S325	[102]
						S354	S327	[102]^b
	Ph	PHC1	HPH1/EDR1	P78364	1,004	Y32	Y32	[113]
						S195	S195	^c
						S645	S653	^c
						S653	S661	[114]
						S657	S665	[114]
						S664	S672	[114]^c
						S669	S677	[114]^c
						S786	S794	^c
						S895	S903	^c
						T918	T926	[103]
						T922	T930	[103]^c
		PHC2	HPH2	Q8IXK0	858	S591	S583	[102]
						T619	T611	[102]
						S621	S613	[103]
						S701	S693	[104]
						S704	S696	[104]
						S733	S725	[115]^c
						S745	S737	[105]
		PHC3	HPH3/EDR3	Q8NDX5	983	S229	S227	[115]
						S263	S261	[105,110]
						S315	S312	[102]^c
						T609	T607^a	[102,103,105,107,109,110]^c
						T614	T612^a	[102,107]^b
						S616	S614^a	[102,103,105,107,109,110]^c
						S724	S722	[102]^b
						S761	S759	[102]
						S762	S760	[102]
						S862	S860	^c
	Sce/dRING	RING1	RING1A/RNF1	Q06587	406	S38	S38	[102,103,107]^c
						S187	S187	[102,103]
						S188	S188	[102,103]
						S190	S190	[102,103]
						S229	S229	^c
		RNF2	RING1B/RING2	Q99496	336	S41	S41	[69]
						S168	S168	[110]
	Psc	BMI1	PCGF4	P35226	326	S251	S249^a	[110]
						S253	S251^a	[110]
						S255	S253^a	[110]
		PCGF2	RNF110/MEL18	P35227	344	Y197	Y197	[113]
						Y205	Y205	[113]
						Y206	Y206	[113]
						T344	gap	[102]
PhoRC	Pho	YY1		P25490	414	S118	S120^a	[109]
						S184	S184	[104]
						S247	S247^a	[102,103,105,108,109]
						Y251	Y251	[102]
						T348	T348	[102,116]
						T378	T378	[102,103]
Other	Psc	PCGF1	NSPc1	Q9BSM1	259	-	-	-
		PCGF6	MBLR/RNF134	Q9BYE7	350	S30^d	S34	[44]
	Scm	SCMH1		Q96GD3	660	S649	S653	[102,114]
		SCML1		Q9UN30	208	S15	NA	[102]^b
						S17	NA	[102]
						S117	NA	[108]
		SCML2		Q9UQR0	700	S255	NA	[102]^b
						S256	NA	[102]
						S258	NA	[102]
						S267	NA	[102]
						S299	NA	[102]
						S300	NA	[102]
						T305	NA	[102]
						S495	NA	[102]^b
						S499	NA	[102,103,105,106]
						T503	NA	[102]
						S511	NA	[102,103,105,106]
						S570	NA	[115]
						S576	NA	[102]
						T581	NA	[102]^b
						S583	NA	[102]
						S590	NA	[102,103]
						S594	NA	[102,103]
						S606	NA	[102]
		RYBP		Q8N488	228	S127	S127	[102]
						S130	S130	[102]
						S203	S203	[102]^b
						T215	T215	[102]^b

^aSites that were detected as phosphorylation sites in mouse cells as well; ^bthese putative phosphorylation sites do not reach a sufficiently high probability based on prediction algorithms used; ^cmarks unpublished results (HN, JD, JWV); ^dsite was referred to as S32 in original article.

NA = not available; NC = non-conserved