Table 1.

Censoring events by drug category for the efficacy analysis (both comparative and non-comparative studies included)

		AS&AQ		Other ACTs		non-ACT
Criteria		n	%	n	%	n	%
Total		5987	100%	2787	100%	2926	100%
Censored on Day 0	- no drug intake			3
	- voluntary withdrawal	19
	- self-medication	10				16
	- protocol violation	16		18			13
Sub-total		5942	99%	2769	99%	2897	99%
Failure	Total recurrent cases	1126	91%	429	95%	1171	95%
	- PCR confirmed*	203		95		436
	- indeterminate*	47		47
	- no PCR/no sample*	20		51		34
	Danger sign/severe malaria/death*	24	2%	8	2%	1	<1%
	Increased parasitaemia or >25% Day3*					45	3%
	Clinician decision*	1	<1%
	Drug vomiting	44	4%	6	1%		<1%
	Still positive when lost to follow-up*	29	2%	5	1%	13	1%
	Lost result*	11	1%	3	1%	8	1%
	Total	1235	100%	451	100%	1238	100%

* Classified as recrudescent failure

ACT: artemisinin combination therapy.