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. Author manuscript; available in PMC: 2010 Jul 15.
Published in final edited form as: Dev Biol. 2009 May 3;331(2):167–175. doi: 10.1016/j.ydbio.2009.04.032

Figure 3. Defects of the outflow tract and AV canal in BMPRIIflox/−;Mox2-Cre mice.

Figure 3

Hematoxylin and eosin staining is shown for control (A, B, C, D) and mutant (E, F, G, H) mice at E16.5. DORV (E, F), VSD (F, arrow), and AV canal defect with abnormal atrial septation (G, H) were observed in BMPRIIflox/−;Mox2-Cre mice. Ao: aorta, P: pulmonary artery, LA: left atrium, RA: right atrium, LV: left ventricle, RV: right ventricle. Scale bars: 0.5 mm (A–H).