Figure 6. Thickened semilunar valves in BMPRIIflox/−;Mox2-Cre and BMPRIIflox/−;Tie2-Cre mice.
(A–D) Hematoxylin and eosin staining is shown for the aortic valve in a control mouse at E17.5 (A), for aortic and pulmonary valves with DORV in a BMPRIIflox/−;Mox2-Cre mouse at E17.5 (B), for a pulmonary valve in a control mouse at P3 (C), and for a pulmonary valve in a BMPRIIflox/−;Tie2-Cre mouse (D). AoV: aortic valve, PV: pulmonary valve. Scale bars: 0.2 mm (A–D).