Table 2.
Levels of N6-HOMe-dAdo (as N6-Me-dAdo) in leukocyte DNA of smokers and non-smokers
| fmol N6-Me-dAdo/µmol dAdo | |||||
|---|---|---|---|---|---|
| Smokers |
Non-smokers |
||||
| 1 | F | 76 | 1 | F | NDa |
| 2 | M | 118 | 2 | F | 36 |
| 3 | M | 72 | 3 | F | ND |
| 4 | F | 151 | 4 | F | ND |
| 5 | M | 116 | 5 | F | ND |
| 6 | M | ND | 6 | F | ND |
| 7 | M | 116 | 7 | F | ND |
| 8 | M | 144 | 8 | M | ND |
| 9 | F | 168 | 9 | F | ND |
| 10 | M | ND | 10 | M | ND |
| 11 | M | 30 | 11 | M | 74 |
| 12 | M | 41 | 12 | M | ND |
| 13 | F | 66 | 13 | M | ND |
| 14 | F | 128 | 14 | M | 23 |
| 15 | M | 25 | 15 | M | ND |
| 16 | M | 303 | 16 | M | ND |
| 17 | F | 94 | 17 | M | ND |
| 18 | M | 180 | 18 | M | ND |
| 19 | F | 195 | 19 | M | 122 |
| 20 | F | 452 | 20 | M | ND |
| 21 | F | 284 | 21 | M | ND |
| 22 | F | 631 | 22 | M | 65 |
| 23 | M | 929 | 23 | F | ND |
| 24 | F | 35 | 24 | F | ND |
| 25 | F | 75 | 25 | F | ND |
| 26 | F | 141 | 26 | F | 32 |
| 27 | F | 33 | 27 | F | ND |
| 28 | F | ND | 28 | F | ND |
| 29 | M | 181 | 29 | M | ND |
| 30 | M | 557 | 30 | F | 114 |
| 31 | M | 302 | Mean ± S.D. | 15.5 ± 33.8 | |
| 32 | F | 95 | (7/30 positive) | ||
| Mean ± S.D. | 179 ± 205 | ||||
| (29/32 positive) | |||||
Levels in smokers were significantly higher than in non-smokers, P<0.001
a
ND = not detected. A value of zero was used to calculate the arithmetic mean shown. Detection limit ≅ 10 fmol/µmol dAdo