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. Author manuscript; available in PMC: 2010 Sep 15.
Published in final edited form as: Cancer Res. 2009 Sep 8;69(18):7262–7269. doi: 10.1158/0008-5472.CAN-09-0604

Figure 3. X-irradiation of mice results in persistent increases in DNA damage in BM cells.

Figure 3

Mice were irradiated at 5 Gy and transferred into cages with water +/- 40μM NAC. At the indicated time-points, mice were sacrificed and BM harvested. A) BM cells were permeabilized and stained with a fluorescent-linked antibody to γH2AX. Representative flow profiles are shown (gray overlay plot: analysis of untreated/control BM). B) Percentages of γH2AX+ cells at the indicated time-points are plotted (5-6 mice/group). C) Leukocyte counts from peripheral blood were determined using automated CBC analysis.