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Histological features of the graft site. Hematoxylin-eosin staining on Nell-1 treated (a, c, e) and PBS treated (b, d, f) spine 4 weeks after implantation. Arrows indicate cortical-natured bone bridges connecting two involved transverse processes identified by dotted lines (a). Cartilaginous tissues (arrowheads) were detected around the demineralized bone matrix material in Nell-1 group (e). Original magnification: 9.8× (a, b) and 100× (c-f).
