Table 2.
Selected references of successful in vivo tumor targeting using fluorescent probes conjugated with the folate-receptor (FR).
| Authors | References | FR-targeted fluorescent probes |
Targeted pathology |
Targeted species |
|---|---|---|---|---|
| Moon et al | Bioconjugate Chem 2003 [21] |
folate targeting NIR fluorochrome |
FR-positive KB cells (Human nasopharyngeal Carcinoma) |
mouse |
| Kennedy et al | J. of Biomed Optics 2003 [22] |
folate-fluorescein conjugate |
FR-positive M109 cells (murine lung carcinoma) and L1210 cells (leukemia cells) |
mouse |
| Chen et al | Molecular Imaging 2005 [23] |
fluorescent folate probe (FFP) |
Activated macrophages on dysplastic intestinal adenomas |
mouse |