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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: J Pediatr. 2008 Jun 4;153(4):525–529. doi: 10.1016/j.jpeds.2008.04.033

Table 2.

Markers of Pulmonary Morbidity after Discharge from the NICU

INO
(%)
Placebo
(%)
OR*
(95%CI)
NNT**
(95% CI)
Wheezing or whistling in the chest 49.6 56.4 0.70 (0.48–1.03) ---
Bronchodilator Use 40.1 54.1 0.53 (0.36–0.78) 6.3 (4.0–15.6)
Inhaled Steroid Use 19.8 32.4 0.50 (0.32–0.77) 7.5 (4.6, 19.6)
Systemic Steroid Use 11.0 17.7 0.56 (0.32–0.97) 14.1 (7.3, 250.0)
Diuretic Use 18.6 28.4 0.54 (0.34–0.85) 9.0 (5.2–33.3)
Any Home O2 Use 38.4 49.5 0.65 (0.44–0.95) 9.4 (5.0, 76.9)
Persistent O2 Use at Time of Follow-Up 3.0 9.4 0.30 (0.13–0.73) 15.9 (9.4–52.6)
Any Hospitalization 46.5 50.4 0.83 (0.57–1.21) ---
Respiratory Hospitalization 22.6 21.9 1.03 (0.65–1.62) ---
*

Odds Ratio

**

Number needed to treat were calculated by GEE. NNT represents the number of patients that would need to be treated with a therapy in order to improve one patient’s outcome. Respiratory hospitalizations included admissions for wheezing and/or respiratory infection.