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. Author manuscript; available in PMC: 2009 Sep 17.
Published in final edited form as: Cell Microbiol. 2006 Jun 7;8(11):1730–1739. doi: 10.1111/j.1462-5822.2006.00742.x

Fig. 7.

Fig. 7

Effects of clumping on the outcome of pulmonary infection. Mice were infected intratracheally with 104 C. neoformans.

A. Fungal burden (cfu) at day 14 post infection; *P = 0.007.

B. Inflammatory immune response in lungs at day 14 post infection (H&E).

C. Alveolar macrophages at day 14 post infection (Mac3). Arrow points to C. neoformans-loaded macrophage.

D. Survival curves for mice infected with clump+ cells and clump− cells. The average survival time of mice infected with clump+ cells and clump− cells was 91 and 76 days respectively (n = 14 per group).