Table 3.
Allele and Genotype Distribution of ADORA2A and DRD2 Polymorphisms for European-American (EA) Participants
| Allele | Genotype | ||||
|---|---|---|---|---|---|
| Polymorphism | 1 | 2 | 1/1 | 1/2 | 2/2 |
| A2A receptor gene | |||||
| rs5751862 | 56 (A) | 68 (G) | 13 (AA) | 30 (AG) | 19 (GG) |
| rs5760405 | 97 (C) | 27 (T) | 38 (CC) | 21 (CT) | 3 (TT) |
| rs2298383 | 55 (C) | 69 (T) | 14 (CC) | 27 (CT) | 21 (TT) |
| rs3761422 | 75 (C) | 49 (T) | 24 (CC) | 27 (CT) | 11 (TT) |
| rs2236624 | 96 (C) | 28 (T) | 38 (CC) | 20 (CT) | 4 (TT) |
| rs5751876a | 73 (C) | 51 (T) | 23 (CC) | 27 (CT) | 12 (TT) |
| rs35320474 | 73 (T) | 51 (−) | 23 (TT) | 27 (T−) | 12(− −) |
| rs4822492 | 69 (G) | 55 (C) | 21 (GG) | 27 (GC) | 14 (CC) |
| DRD2 receptor gene | |||||
| rs1799978 | 98 (A) | 10 (G) | 45 (AA) | 8 (AG) | 1 (GG) |
| rs1799732 | 98 (C) | 12 (−) | 43 (CC) | 12 (C−) | − (− −) |
| rs1079597 | 9 (A) | 95 (G) | − (AA) | 9 (AG) | 43 (GG) |
| rs1800498 | 44 (G) | 64 (A) | 6 (GG) | 32 (GA) | 16 (AA) |
| rs1110976 | 95 (G) | 15 (−) | 42 (GG) | 11 (G−) | 2 (− −) |
| rs6275 | 71 (C) | 39 (T) | 21 (CC) | 29 (CT) | 5 (TT) |
| rs6279 | 40 (C) | 70 (G) | 6 (CC) | 28 (CG) | 21 (GG) |
| rs1800497 | 90 (C) | 18 (T) | 38 (CC) | 14 (CT) | 2 (TT) |
a
Values for individuals from all population groups are alleles 101(C), 103(T); genotypes 29(CC), 43(CT), 30 (TT).