Table 1.

The signature of 25 genes for characterizing lung cancer subtypes. Enrichment shows that there are 23 unique genes in the signature.

Gene symbol	Gene title	Pathway
ABCC3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	ABC transporters
BICD2	bicaudal D homolog 2 (Drosophila)
CDA	cytidine deaminase	Pyrimidine metabolism, Drug metabolism
CLDN3	claudin 3	Cell adhesion molecules, Tight junction, Leukocyte transendothelial migration
DPP4	dipeptidyl-peptidase 4
HGD	homogentisate 1,2-dioxygenase (homogentisate oxidase)	Tyrosine metabolism, Styrene degradation
ITPKA	inositol 1,4,5-trisphosphate 3-kinase A	Inositol phosphate metabolism, Calcium signaling pathway, Phosphatidylinositol signaling system
KRT14	keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner)	Cell communication
KRT6A, KRT6B, KRT6C	keratin 6A, keratin 6B, keratin 6C,	Cell communication
MUC3B	mucin 3B, cell surface associated
MUC5B	mucin 5B, oligomeric mucus/gel-forming
NMNAT2	nicotinamide nucleotide adenylyltransferase 2	Nicotinate and nicotinamide metabolism
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	MAPK signaling pathway
RHCG	Rh family, C glycoprotein
SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13
SOX2	SRY (sex determining region Y)-box 2
SPINK1	serine peptidase inhibitor, Kazal type 1
SPRR1A	small proline-rich protein 1A
TJP3	tight junction protein 3 (zona occludens 3)	Tight junction
TOX3	TOX high mobility group box family member 3
VSNL1	visinin-like 1