Table 1.
Classification for chronic renal diseases | Exp. | Ctrl. |
"Predominant" Inflammatory | ||
IgA Nephropathy (IgAN) | 25 | 6 |
Systemic lupus erythematosus (SLE) | 32 | 15 |
"Predominant" Non-Inflammatory | ||
Focal & segmental glomerulosclerosis (FSGS) | 10 | 15 |
Membranous glomerulonephritis (MGN) | 18 | 15 |
Minimal change disease (MCD) | 4 | 3 |
Thin membrane disease (TMD) | 6 | 3 |
"Predominant" Metabolic | ||
Diabetic nephropathy (DN) | 11 | 3 |
Total | 106 | 60 |
The dataset consisted of biopsies from 106 patients diagnosed with one of 7 renal diseases, and compared with biopsies from 60 healthy patients within the same expression analysis batch. A test of significance between the two groups resulted in 747 genes implicated across the 7 chronic renal diseases.