Figure 7. Dicyanocobinamide inhibition of NO formation by mouse macrophages.
Cells of the mouse macrophage cell line Raw 264.7 were incubated 24 hours with 500 units/ml murine interferon gamma to activate them for NO production. The cultures also contained 0, 0.5, 2.0, or 8.0 μM dicyanocobinamide for the entire culture period. At the end of the culture period, the cells were assessed for NO production using DAF-FM and a fluorimeter. Results are expressed as NO production (percent of control). The error bars show the SEM. This is from 6 separate experiments.
